Sunday, January 5, 2020

Benefits of Ashwagandha


Benefits of Ashwagandha

Ashwagandha is an ancient medicinal herb.

It’s classified as an adaptogen, meaning that it can help your body manage stress.

Ashwagandha also provides numerous other benefits for your body and brain.
“Horse Smell”
"Ashwagandha" is Sanskrit for "smell of the horse," which refers to both its unique smell and ability to increase strength.
The ashwagandha plant is a small shrub with yellow flowers that's native to India and North Africa. Extracts or powder from the plant's root or leaves are used to treat a variety of conditions


Ashwagandha, also known as Indian ginseng, has a wide range of health benefits, which include its ability to reduce the blood sugar levels, and cortisol levels, fight cancer, reduce stress and anxiety, and increase fertility in men.

It has been used for over 3,000 years to relieve stress,increase energy levels, and improve concentration.

It also helps prevent arthritis, asthma, hypertension, and rheumatism. Furthermore, Ashwagandha boosts the supply of antioxidants and regulates the immune system. What’s more? It also has antibacterial and anticonvulsant properties.
Traditional Uses
In the Indian traditional medicine system of Ayurveda, ashwagandha is seen as a broad-spectrum remedy. It’s classified as a Rasayana or rejuvenator. These are some of the traditional uses [2, 4, 5]:
  • The roots are used as a tonic, aphrodisiac, diuretic, antiparasitic, astringent, and stimulant
  • The leaves are recommended for fever and painful swelling
  • The seeds are antiparasitic while the flowers are used as an astringent, diuretic, and aphrodisiac and have detoxifying effects
  • The berries and tender leaves are applied externally to tumors, ulcers, and wounds
  • Other useful parts are the stem, fruit, and bark
What is Ashwagandha (Indian Ginseng)?
Ashwagandha (Withania somnifera) is a medicinal herb that has been used in Ayurvedic and Chinese medicine for thousands of years. It is an adaptogen, which means that it has the ability to help the body to manage stress. 
It belongs to the Solanaceae family and is also known as Indian ginseng or winter   cherry.
The use of Ashwagandha for so many centuries has aroused the curiosity of modern medical science, leading to an interest in investigating the medicinal properties of the plant. Preliminary studies indicated the presence of potential therapeutic abilities and it also showed no associated toxicity to the chemical constituents of the plant.
A 2011 scientific report on the plant, published in the Journal of Stress Physiology & Biochemistry, indicates that it has anti-inflammatory, anti-oxidizing, anti-stress, sleep-inducing, and drug withdrawal properties. Many formulations that are made from this herb improve musculoskeletal problems such as arthritis and rheumatism. It also acts as a tonic that boosts energy and improves overall health and longevity.
Research conducted at the National Institute of Advanced Industrial Science and Technology in Japan reported that the leaves of Ashwagandha can selectively inhibit cancer cells. So why has this herb been so popular and why is everyone talking about it?
Health Benefits of Ashwagandha
Controls Blood Sugar Levels
Ashwagandha has long been used for diabetes in Ayurvedic medicine. A research report published in the International Journal of Molecular Sciences revealed that the flavonoids found in the roots and leaves of ashwagandha are used to cure diabetes. As part of the experiment, diabetic rats were administered with the extracts of W. somnifera root (WSREt) and leaf (WSLEt). It was concluded that ashwagandha possesses antidiabetic and antihyperlipidemic properties that significantly decrease the blood sugar levels in diabetic rats during fasting and the post-lunch period when consumed for 4 weeks or more.
Animal studies have found that it significantly decreases levels of these blood fats.
One study in rats found that it lowered total cholesterol and triglyceride levels by 53% and nearly 45%, respectively (28Trusted Source). While controlled human studies have reported less dramatic results, they have observed some impressive improvements in these markers (3, 4Trusted Source, 5Trusted Source, 6Trusted Source).
In a 60-day study in chronically stressed adults, the group taking the highest dosage of standardized ashwagandha extract experienced a 17% decrease in LDL (bad) cholesterol and an 11% decrease in triglycerides, on average (3).
 Controls Cholesterol Levels and triglycerides
Ashwagandha root, with its anti-inflammatory and anti-oxidant properties, is good for cardiovascular problems. It strengthens the  heart  muscles and can also control cholesterol. A study published by the University of Arizona in the World Journal of Medical Sciences indicates that it possesses hypolipidemic properties that help in bringing down blood cholesterol levels.                  
Relieves Stress
Ashwagandha extract is believed to reduce the cortisol levels in the body and thereby possesses anti-stress properties. Traditionally, it had been administered to induce a soothing and calming effect on a person. A study published in the Indian Journal of Clinical Biochemistry found that laboratory rats treated with the herbal extract of Ashwagandha could withstand multiple stress tests that they were subjected to, as compared to a passive control group.
Can reduce cortisol levels
Cortisol is known as a stress hormone given that your adrenal glands release it in response to stress, as well as when your blood sugar levels get too low.
Unfortunately, in some cases, cortisol levels may become chronically elevated, which can lead to high blood sugar levels and increased fat storage in the abdomen.
Studies have shown that ashwagandha may help reduce cortisol levels(3, 14Trusted Source, 15Trusted Source).
In one study in chronically stressed adults, those who supplemented with ashwagandha had significantly greater reductions in cortisol, compared with the control group. Those taking the highest dose experienced a 30% reduction, on average (3).

 Reproductive Health

Women
Ashwagandha may reduce the complications of menopause. In a trial of 51 menopausal women, ashwagandha reduced symptoms such as hot flashes, mood fluctuations, sleep issues, irritability, and anxiety [68].
In 50 healthy women, Ashwagandha improved self-reported measures of sexual function such as arousal, lubrication, orgasm, and satisfaction [69].
Ashwagandha with Tribulus terrestris restored hormone balance in rats with polycystic ovary syndrome (PCOS) [70
Ashwagandha root is also used to restore health in women after giving birth and to thicken and increase the nutrition of breast milk. Despite its centuries-long use in India, Ashwagandha has only recently gained scientific recognition in the West [6, 2].
Can boost testosterone and increase fertility in men
In addition to increasing the testosterone levels, Ashwagandha also helps in improving the semen quality. A 2010 scientific study published by the American Center for Reproductive Medicine indicated
that Ashwagandha
plays an important role as an aphrodisiac as well as a way to improve semen quality by increasing sperm count and sperm mobility. This has been the reason why, for many centuries, people have been using it as a medication to please their partner in bed.
In a clinical trial of 150 men, Ashwagandha reduced oxidative stress, increased   testasterone, and lowered FSH. These hormonal changes encourage the production of new sperm cells. It also improved sperm count and mobility [71].
In 46 men with low sperm count, Ashwagandha increased [72]:
  • sperm count, by 167%
  • semen volume, by 53%
  • sperm motility, by 57%
It recovered semen quality in 180 infertile men [73].
Aids in Muscle Growth
Ashwagandha has been found to be useful in improving the muscular strength of the lower limbs and helping recover weakness. It also has a positive impact on neuro-muscular coordination.
Helps with Erectile Dysfunction
Suffering from erectile dysfunction? Intake of Ashwagandha for libido and sexual health is a traditional Ayurveda remedy however, there are not many scientific studies supporting the claim.
Note: It should be used for ED only under the recommendation of a professional medical practitioner.
Stimulates the Thyroid Gland
In cases of Hypothyroid, Ashwagandha can be used to stimulate the thyroid gland. A 2011 study published in the Journal of Pharmacy and Pharmacology on its effects on the thyroid gland revealed that the root extract if given on a daily basis, would increase the secretion of thyroid hormones.
Boosts Immunity
Research studies have shown that the consumption of Ashwagandha led to significant modulation of immune system reactivity and prevented myelosuppression in mice induced by immunosuppressive drugs. Ashwagandha capsules can help increase the red blood cell, white blood cell, and platelet count, which in turn help boost immunity.
Increases Blood Production
Hematopoiesis is the process of producing new blood. According to research published in Alternative Medicine Review, Ashwagandha possesses hematopoietic properties. The study showed that red blood cell and white blood cell counts increased significantly in rats which were administered with the herb. This could mean a positive effect on human red blood cells as well, thereby helping to prevent conditions like anemia.
 Gut Health
In a single case report, an Ayurvedic medication containing Ashwagandha helped treat constipation, stomach pain, and vomiting [87].
An enema of Ashwagandha restored the health of the intestinal lining in rats with IBD [88].
Note, however, that one animal study and a single case study of an herbal blend cannot be considered strong evidence. We need additional studies before making any definitive claims about Ashwagandha’s effect on the digestive system.
Liver Health
Ashwagandha protected the liver against damage from radiation and heavy metals in rats [126, 127].
It increased the bile content in rats with high cholesterol and decreased certain liver enzymes that indicate tissue damage [39, 128].
Respiratory Health
Polysaccharides extracted from Ashwagandha suppressed coughing in guinea pigs as effectively as codeine [129, 130].
In baby rats, withaferin A also protected the lungs against inflammation and oxidative stress caused by toxic bacterial lipopolysaccharides (LPS). Future trials will clarify whether Ashwagandha or its compounds may be helpful against respiratory infections [131].
Autoimmunity
Lupus is an autoimmune disease that involves high levels of inflammation. In a mouse study, Ashwagandha reduced inflammatory markers that tend to be high in lupus and other autoimmune diseases, including IL-6 and TNF-alpha [132, 133].
Morphine Dependence
Ashwagandha may help prevent people from developing a dependence on morphine, and it may help people who are already dependent wean themselves off of morphine without severe withdrawal symptoms [136].
In a rat study, Ashwagandha extract reduced withdrawal symptoms and prevented morphine dependence. In neurons exposed directly to morphine, Ashwagandha extract prevented the downregulation of opioid receptor activity. Thus, Ashwagandha may be useful to prevent dependence when opioid painkillers are necessary [137, 138, 136].
Mild Hypothyroidism
Mild  hypothyrodisim, or low thyroid hormones , occurs in 3-8% of people and is especially common in women over 55. Treatment with levothyroxine, a synthetic form of the thyroid hormone T4, often comes with more risks than benefits; thus, many people with mild hypothyroidism go untreated [139].
In a trial of 50 people with mild hypothyroidism, Ashwagandha extract normalized TSH and thyroid hormones (T3 and T4) [140].
It also increased thyroid hormones in hypothyroid rodents and reduced oxidative stress and inflammation [141, 141, 142].
Prevents Seizures
Ashwagandha natural herbal formula and extracts have been a widely used remedy for seizures and convulsions in Ayurvedic medicine. Another study, published in the Indian Journal of Clinical Biochemistry, also showed the presence of anticonvulsant properties in this wonderful plant.
Reduces Ocular Diseases

The antioxidant and cytoprotective properties of Ashwagandha are ideal for fighting cataract diseases.

Fights Cancer
In a research study published in the Alternative Medicine Review, naturopathic doctor Marie Winters has described ashwagandha as an emerging and novel alternative in the field of oncology, in association with radiation therapy and chemotherapy, because of its cancer-killing properties. It is also of interest because it is known to reduce the side effects of chemotherapy without interfering with the tumor cell-killing activity.
 Cancer Research
Ashwagandha improved fatigue and quality of life in a trial of 100 cancer patients receiving chemotherapy [143].
Several animal and cell studies have shown that the constituents of Ashwagandha, in particular withaferin A, inhibit or destroy cancer cells [144, 2, 145, 10].
What’s more, Ashwagandha can make the chemotherapy drug paclitaxel more effective against lung cancer, according to mouse studies [146, 147, 148].
In cell and animal studies, Ashwagandha has slowed or reversed the growth of several cancers, including:

Anti-inflammatory Properties

Ashwagandha has been found to be effective in dealing with a variety of rheumatologic problems. The herb is known to act as a cyclooxygenase inhibitor that decreases inflammation and pain. Research conducted at the Los Angeles College of Chiropractors suggests that the herb has anti-inflammatory properties that come from the alkaloids, saponins, and steroidal lactones found within it.
Antibacterial Properties
According to Ayurvedic medical texts, Ashwagandha is effective in controlling bacterial infections in humans. A 2011 study, published in the Alternative Medicine Review, showed that this herb possesses antibacterial properties. It also concluded that it was effective in urinogenital, gastrointestinal, and respiratory tract infections when consumed orally.
Side Effects of Using Ashwagandha
Pregnant Women: Pregnant women are advised to avoid the consumption of this herb as it possesses abortifacient properties.
Medical Interactions: Doctors advise caution because it can interact with regular medications, especially for those who are suffering from diseases like diabetes, hypertension, anxiety, depression, and insomnia.
Gastrointestinal problems:
Avoid consumption in large amounts as this may have side effects such as           
diarrhea , upset stomach, and nausea.

How to Use Ashwagandha

Dosage

The root is available in the market in powdered, dried, or fresh root form. 1-2 tsp or 5-6 grams of the powder is recommended when you consume it for general well being. You can also take Ashwagandha for anxiety relief. You could also consume organic Ashwagandha root powder, along with a glass of hot milk and  mix with honey  before going to sleep. However, when you take the herb for treating any specific disease you should consult a medical professional such as an Ayurvedic doctor for the dosage.

How to Use Ashwagandha

Dosage
There is no safe and effective dose of ashwagandha because no sufficiently powered study has been conducted to find one.
Root extract: most clinical studies have used 120-1000 mg daily, with the most common dose being 300 mg twice daily.
Whole root: clinical doses range between 2-10 g of powdered root daily, with an average of 5 g per day.
Ashwagandha tea: You can make the tea by boiling the powder in water for 10 minutes. Don’t use more than a teaspoon in one cup of water.

Supplement Forms

Ashwagandha is available in many forms, such as powder, capsules, pills, or essential oil. It can also be made into a tea or ointment using honey or ghee. Commercial Ashwagandha is often combined with black pepper extract,another strong antioxidant.
In Ayurveda, the fresh roots are sometimes boiled in milk prior to drying to leach out undesirable components [167].

Taste & Smell

Ashwagandha is a famously pungent herb. Its name means “smell of horse”, and some users say it can be overwhelming. If you are concerned about the smell and taste of Ashwagandha but still want to try it, look for capsules of dry extracts [3, 2].
Is safe for most people and widely available
Ashwagandha is a safe supplement for most people, although its long-term effects are unknown.
However, certain individuals should not take it, including pregnant and breastfeeding women.
People with autoimmune diseases should also avoid ashwagandha unless authorized by a healthcare provider. This includes people with conditions like rheumatoid arthritis, lupus, Hashimoto's thyroiditis, and type 1 diabetes.
·         Additionally, those on medication for thyroid disease should be careful when taking ashwagandha, as it may increase thyroid hormone levels in some people.
·         It may also decrease blood sugar and blood pressure levels, so medication dosages may need to be adjusted if you take it.
·         The recommended dosage of ashwagandha depends on the type of supplement. Extracts are more effective than crude ashwagandha root or leaf powder. Remember to follow instructions on labels.
·         Standardized root extract is commonly taken in 450–500-mg capsules once or twice daily.
·         It’s offered by several supplement manufacturers and available from various retailers, including health food stores and vitamin shops.
·         There's also a great selection of high-quality supplements available online.
·         Summary Although ashwagandha is safe for most people, certain individuals shouldn't use it unless authorized to do so by their healthcare provider. Standardized root extract is commonly taken in 450–500-mg capsules once or twice per day.

The bottom line

·         Ashwagandha is an ancient medicinal herb with multiple health benefits.
·         It can reduce anxiety and stress, help fight depression, boost fertility and testosterone in men, and even boost brain function.
·         Supplementing with ashwagandha may be an easy and effective way to improve your health and quality of life.